研究室概况:
杂粮营养与功能效用研究团队一直秉承以杂粮的安全性、有效性和可控性为目标,系统性地开展杂粮的营养功能与安全性研究工作。近年来,先后承担了国家、省市级重大科研项目20余项;出版《荞麦的营养与功能》等学术专著3部;发表学术论文80余篇,其中SCI收录20余篇;获四川省科技进步一等奖等奖励8项。团队成员基于多年研究成果,联合杂粮相关企业大力研发了多种杂粮加工新产品新技术,实现了科研成果转化产值20亿元以上,引领地区现代农业发展和新农村建设。
杂粮营养与功能效用研究室主要由动物饲养间、动物解剖间、细胞室、光谱室、色谱室等组成。研究室拥有分析型流式细胞仪、全自动蛋白定量分析系统、高分辨飞行时间液质联用仪、电感耦合等离子体质谱仪、感官分析系统(电子鼻、电子舌、电子眼)、气相质谱联用仪、多功能微孔板检测仪、傅里叶红外光谱仪、氨基酸分析仪、超高效液相色谱仪、高效液相色谱仪等精密分析设备,价值1200余万元。本研究室具备开展杂粮功能成分分析、安全性评价、杂粮营养功效评价及其作用机制探索等方面研究的硬件条件。
研究方向与主要研究内容:
获奖情况:
1. 四川省科学技术进步一等奖:优质专用甘薯产业关键技术创新与集成推广
2. 神农中华农业科技奖二等奖:四川及周边特困地区马铃薯产业关键技术创新与推广
3. 中华农业科技奖三等奖:马铃薯高效种植模式与周年生产关键技术
4. 四川省科学技术进步奖三等奖:马铃薯不同世代脱毒种薯生长发育特性与高效扩繁关键技术
主要科研项目:
1. 国家自然科学基金青年科学基金项目:姜黄挥发油气调用于贮藏期种子类中药抗黄曲霉污染的质量控制综合评价(项目编号:81603288)
2. 四川省应用基础研究项目:葛根芩连汤拮抗伊立替康肠毒性的质量属性辨识研究(项目编号:2020YJ0195)
3. 中国博士后科学基金第62批面上项目:中药中铅、镉离子残留的纳米荧光可视化检测技术研究(项目编号:2017M620418)
4. 四川省中医药管理局花椒专项项目:花椒油固体气调剂抗中药材贮藏过程黄曲霉菌污染研究(项目编号:2018HJZX007)
5. 四川省教育厅科研项目:基于肠道菌群结构调整的藜麦多糖抗高脂血症作用机理研究(项目编号:17ZB0113)
代表性论文:
1. Yichen Hu, Jinming Zhang, Weijun Kong, Gang Zhao, Meihua Yang*. Mechanisms of antifungal and anti-aflatoxigenic properties of essential oil derived from turmeric (Curcuma longa L.) on Aspergillus flavus. Food Chemistry, 2017, 220, 1–8. (IF=6.308,高被引)
2. Yanan Cao, Liang Zou, Wei Li, Yu Song, Gang Zhao, Yichen Hu*. Dietary quinoa (Chenopodium quinoa Willd.) polysaccharides ameliorate high-fat diet-induced hyperlipidemia and modulate gut microbiota [J]. International Journal of Biological Macromolecules, 2020, 163: 55–65. (IF= 5.162)
3. Zheyu Li, Shibo Lin, Siyi An, Lu Liu, Yichen Hu*, Li Wana**. Preparation, characterization and anti-aflatoxigenic activity of chitosan packaging films incorporated with turmeric essential oil [J]. International Journal of Biological Macromolecules, 2019, 131: 420-434. (IF= 5.162)
4. Guixing Ren, Yichen Hu*, Jinming Zhang, Liang Zou, Gang Zhao. Determination of Multi-Class Mycotoxins in Tartary Buckwheat by Ultra-Fast Liquid Chromatography Coupled with Triple Quadrupole Mass Spectrometry [J]. Toxins, 2018, 10, 28. (IF= 3.531)
5. Xuewei Ma†, Yichen Hu†, Xin Li, Xiaoting Zheng, Yitao Wang, Jinming Zhang*, Chaomei Fu*, Funeng Geng*. Periplaneta americana Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Keap1/Nrf-2 Activation, Intestinal Barrier Function, and Gut Microbiota Regulation [J]. Frontiers in Pharmacology, 2018, 9:944. (IF= 4.225)
6. Yichen Hu†, Jinming Zhang†, Liang Zou, Chaomei Fu, Peng Li*, Gang Zhao*. Chemical characterization, antioxidant, immune-regulating and anticancer activities of a novel bioactive polysaccharide from Chenopodium quinoa seeds. International Journal of Biological Macromolecules, 2017, 99, 622–629. (IF= 5.162)
7. Yichen Hu, Xiao Gong*, Jinming Zhang, Fengqian Chen, Chaomei Fu, Peng Li, Liang Zou, Gang Zhao*. Activated Charge-Reversal Polymeric Nano-System: The Promising Strategy in Drug Delivery for Cancer Therapy, Polymers, 2016, 8, 99. (IF= 3.426)
8. Huang J, Luo Y, Zhou B, et al. Growth and Survival of Salmonella enterica and Listeria Monocytogenes on Fresh-cut Produce and Their Juice Extracts: Impacts and Interactions of Food Matrices and Temperature Abuse Conditions[J]. Food Control, 2019,100:300 – 304. (IF= 4.258)
9. Huang J, Qu H, Shen X. Characterization of the complete mitochondrial genome of biocontrol yeast Sporobolomyces sp. (Sporidiobolales: Sporidiobolaceae) with phylogenetic analysis[J]. Mitochondrial DNA Part B, 2020, 5(3):3057-3059. (IF= 0.885)
10. Yuanhang Ren, Lidan Lu, Maoling Tan, Yanan Cao, Lianxin Peng*. Characterization of the complete mitochondrial genome of Meira sp. (Exobasidiales: Brachybasidiaceae) with phylogenetic analysis. Mitochondrial DNA Part B Resources. 2020, 5:3, 2607-2608. (IF= 0.885)
11. Yuanhang Ren#, Jiaxing Shi#, Yangping Mu, Hong Jin*, Ke Tao, Taiping Hou. AW1 neuronal cell cytotoxicity: the mode of action of insecticidal fatty acids. Journal of Agricultural and Food Chemistry. 2019, 67, 43, 12129-12136. (IF= 4.192)
12. Yuanhang Ren, Qiang Li, Lidan Lu, Hong Jin, Ke Tao*, Taiping Hou*. Isochamaejasmin induces toxic effects on Helicoverpa zea via DNA damage and mitochondria-associated apoptosis. Pest Management Science. 2020. (Online)
13. Yuanhang Ren, Qiang Li, Lidan Lu, Hong Jin, Ke Tao*, Taiping Hou*. Toxicity and physiological actions of biflavones on potassium current in insect neuronal cells. Pesticide Biochemistry & Physiology. 2020. (Accept)
14. Huang J, Wang P, Zou L, et al. Effect Mechanism of New Varieties and Technologies on Greening Development of Tartary Buckwheat Industry [M]// Proceedings of the Fourteenth International Conference on Management Science and Engineering Management. 2021:755-762.